| dc.contributor.author | Hart, MG | |
| dc.contributor.author | Grant, R | |
| dc.contributor.author | Garside, R | |
| dc.contributor.author | Rogers, G | |
| dc.contributor.author | Somerville, M | |
| dc.contributor.author | Stein, Ken | |
| dc.date.accessioned | 2013-10-21T10:12:57Z | |
| dc.date.issued | 2008-07-16 | |
| dc.description.abstract | Standard treatment for high grade glioma (HGG) usually entails biopsy or surgical resection where possible followed by radiotherapy. Systemic chemotherapy is usually only given in selected cases and its use is often limited by side effects. Implanting wafers impregnated with chemotherapy agents into the resection cavity represents a novel means of delivering drugs to the central nervous system (CNS) with fewer side effects. It is not clear how effective this modality is or whether it should be recommended as part of standard care for HGG. | en_GB |
| dc.identifier.citation | Issue 3, art. no. CD007294 | en_GB |
| dc.identifier.doi | 10.1002/14651858.CD007294 | |
| dc.identifier.uri | http://hdl.handle.net/10871/13847 | |
| dc.language.iso | en | en_GB |
| dc.publisher | Cochrane Collaboration | en_GB |
| dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/18646178 | en_GB |
| dc.subject | Antineoplastic Agents, Alkylating | en_GB |
| dc.subject | Brain Neoplasms | en_GB |
| dc.subject | Carmustine | en_GB |
| dc.subject | Combined Modality Therapy | en_GB |
| dc.subject | Glioma | en_GB |
| dc.subject | Humans | en_GB |
| dc.subject | Neoplasm Recurrence, Local | en_GB |
| dc.subject | Randomized Controlled Trials as Topic | en_GB |
| dc.title | Chemotherapeutic wafers for High Grade Glioma | en_GB |
| dc.type | Article | en_GB |
| dc.date.available | 2013-10-21T10:12:57Z | |
| exeter.place-of-publication | England | |
| dc.description | This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2008, Issue 3. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review. | en_GB |
| dc.identifier.journal | Cochrane Database of Systematic Reviews | en_GB |
