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dc.contributor.authorHart, MG
dc.contributor.authorGrant, R
dc.contributor.authorGarside, R
dc.contributor.authorRogers, G
dc.contributor.authorSomerville, M
dc.contributor.authorStein, Ken
dc.date.accessioned2013-10-21T10:12:57Z
dc.date.issued2008
dc.description.abstractStandard treatment for high grade glioma (HGG) usually entails biopsy or surgical resection where possible followed by radiotherapy. Systemic chemotherapy is usually only given in selected cases and its use is often limited by side effects. Implanting wafers impregnated with chemotherapy agents into the resection cavity represents a novel means of delivering drugs to the central nervous system (CNS) with fewer side effects. It is not clear how effective this modality is or whether it should be recommended as part of standard care for HGG.en_GB
dc.identifier.citationCochrane Database of Systematic Reviews, 2008, Issue 3, art. no. CD007294en_GB
dc.identifier.doi10.1002/14651858.CD007294
dc.identifier.urihttp://hdl.handle.net/10871/13847
dc.language.isoenen_GB
dc.publisherCochrane Collaborationen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/18646178en_GB
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007294/abstracten_GB
dc.subjectAntineoplastic Agents, Alkylatingen_GB
dc.subjectBrain Neoplasmsen_GB
dc.subjectCarmustineen_GB
dc.subjectCombined Modality Therapyen_GB
dc.subjectGliomaen_GB
dc.subjectHumansen_GB
dc.subjectNeoplasm Recurrence, Localen_GB
dc.subjectRandomized Controlled Trials as Topicen_GB
dc.titleChemotherapeutic wafers for High Grade Gliomaen_GB
dc.typeArticleen_GB
dc.date.available2013-10-21T10:12:57Z
exeter.place-of-publicationEngland
dc.descriptionaddresses: Clinical Neurosciences, Bramwell Dott Building, Western General Hospital, Crewe Road, Edinburgh, Midlothian, UK, EH4 2XU. m.g.hart@doctors.net.uken_GB
dc.descriptiontypes: Journal Article; Meta-Analysis; Reviewen_GB
dc.descriptionThis review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2008, Issue 3. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.en_GB
dc.identifier.journalCochrane Database of Systematic Reviewsen_GB


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