dc.contributor.author | Vaughan, S | |
dc.contributor.author | Dawe, HR | |
dc.date.accessioned | 2013-11-15T14:19:01Z | |
dc.date.issued | 2011-01 | |
dc.description.abstract | Centrioles are found in nearly all eukaryotic cells and are required for growth and maintenance of the radial array of microtubules, the mitotic spindle, and cilia and flagella. Different types of microtubule structures are often required at different places in a given cell; centrioles must move around to nucleate these varied structures. Here, we draw together recent data on diverse centriole movements to decipher common themes in how centrioles move. Par proteins establish and maintain the required cellular asymmetry. The actin cytoskeleton facilitates movement of multiple basal bodies. Microtubule forces acting on the cell cortex, and nuclear-cytoskeletal links, are important for positioning individual centrosomes, and during cell division. Knowledge of these common mechanisms can inform the study of centriole movements across biology. | en_GB |
dc.identifier.citation | Trends in Cell Biology, 2011, Vol. 21, Issue 1, pp. 57 - 66 | en_GB |
dc.identifier.doi | 10.1016/j.tcb.2010.09.004 | |
dc.identifier.other | S0962-8924(10)00198-4 | |
dc.identifier.uri | http://hdl.handle.net/10871/13954 | |
dc.language.iso | en | en_GB |
dc.publisher | Elsevier | en_GB |
dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/20961761 | en_GB |
dc.relation.url | http://www.cell.com/trends/cell-biology/abstract/S0962-8924(10)00198-4?switch=standard | en_GB |
dc.subject | Actins | en_GB |
dc.subject | Animals | en_GB |
dc.subject | Centrioles | en_GB |
dc.subject | Centrosome | en_GB |
dc.subject | Humans | en_GB |
dc.subject | Mitotic Spindle Apparatus | en_GB |
dc.subject | Nuclear Envelope | en_GB |
dc.title | Common themes in centriole and centrosome movements. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2013-11-15T14:19:01Z | |
exeter.place-of-publication | England | |
dc.description | addresses: School of Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford, OX3 0BP, UK. | en_GB |
dc.description | Copyright © 2011 Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in Trends in Cell Biology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Trends in Cell Biology, 2011, Vol. 21, Issue 1, pp. 57 – 66 DOI: 10.1016/j.tcb.2010.09.004 | en_GB |
dc.identifier.journal | Trends in Cell Biology | en_GB |