dc.contributor.author | Willies, SC | |
dc.contributor.author | Isupov, MN | |
dc.contributor.author | Garman, EF | |
dc.contributor.author | Littlechild, JA | |
dc.date.accessioned | 2013-11-18T10:24:59Z | |
dc.date.issued | 2009-02 | |
dc.description.abstract | The crystal structure of Escherichia coli bacterioferritin has been solved to 1.9 A, and shows the symmetrical binding of a haem molecule on the local twofold axis between subunits and a pair of metal atoms bound to each subunit at the ferroxidase centre. These metals have been identified as zinc by the analysis of the structure and X-ray data and confirmed by microfocused proton-induced X-ray emission experiments. For the first time the haem has been shown to be linked to both the internal and the external environments via a cluster of waters positioned above the haem molecule. | en_GB |
dc.identifier.citation | Journal of Biological Inorganic Chemistry, 2009, Vol. 14, Issue 2, pp. 201 - 207 | en_GB |
dc.identifier.doi | 10.1007/s00775-008-0438-8 | |
dc.identifier.uri | http://hdl.handle.net/10871/13960 | |
dc.language.iso | en | en_GB |
dc.publisher | Springer Verlag | en_GB |
dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/18946693 | en_GB |
dc.relation.url | http://link.springer.com/article/10.1007%2Fs00775-008-0438-8 | en_GB |
dc.subject | Bacterial Proteins | en_GB |
dc.subject | Binding Sites | en_GB |
dc.subject | Ceruloplasmin | en_GB |
dc.subject | Crystallography, X-Ray | en_GB |
dc.subject | Cytochrome b Group | en_GB |
dc.subject | Escherichia coli | en_GB |
dc.subject | Ferritins | en_GB |
dc.subject | Heme | en_GB |
dc.subject | Models, Molecular | en_GB |
dc.subject | Molecular Structure | en_GB |
dc.subject | Protein Conformation | en_GB |
dc.subject | Zinc | en_GB |
dc.title | The binding of haem and zinc in the 1.9 A X-ray structure of Escherichia coli bacterioferritin. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2013-11-18T10:24:59Z | |
dc.identifier.issn | 0949-8257 | |
exeter.place-of-publication | Germany | |
dc.description | addresses: School of Biosciences, Henry Wellcome Building for Biocatalysis, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK. | en_GB |
dc.description | types: Journal Article; Research Support, Non-U.S. Gov't | en_GB |
dc.description | This a post-print, author-produced version of an article accepted for publication in Journal of Biological Inorganic Chemistry . Copyright © 2008 Springer Verlag / SBIC . The definitive version is available at http://link.springer.com/article/10.1007%2Fs00775-008-0438-8 | en_GB |
dc.identifier.journal | Journal of Biological Inorganic Chemistry | en_GB |