Improved genetic testing for monogenic diabetes using targeted next-generation sequencing
Lango Allen, H
De Franco, E
Shepherd, Maggie H.
Hattersley, Andrew T.
Weedon, Michael N.
Current genetic tests for diagnosing monogenic diabetes rely on selection of the appropriate gene for analysis according to the patient's phenotype. Next-generation sequencing enables the simultaneous analysis of multiple genes in a single test. Our aim was to develop a targeted next-generation sequencing assay to detect mutations in all known MODY and neonatal diabetes genes.
addresses: Institute for Biomedical and Clinical Science, University of Exeter Medical School, Barrack Road, Exeter EX2 5DW, UK. email@example.com
notes: PMCID: PMC3737433
types: Journal Article; Research Support, Non-U.S. Gov't
Open Access Article
Diabetologia, 2013, Vol. 56, Issue 9, pp. 1958 - 1963
Place of publication