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Falling threshold for treatment of borderline elevated thyrotropin levels-balancing benefits and risks: evidence from a large community-based study

dc.contributor.authorTaylor, PN
dc.contributor.authorIqbal, A
dc.contributor.authorMinassian, C
dc.contributor.authorSayers, A
dc.contributor.authorDraman, MS
dc.contributor.authorGreenwood, R
dc.contributor.authorHamilton, W
dc.contributor.authorOkosieme, O
dc.contributor.authorPanicker, V
dc.contributor.authorThomas, SL
dc.contributor.authorDayan, Colin M.
dc.date.accessioned2014-08-13T14:27:17Z
dc.date.issued2014-01
dc.description.abstractRates of thyroid hormone prescribing in the United States and the United Kingdom have increased substantially. If some of the increase is due to lowering the thyrotropin threshold for treatment, this may result in less benefit and greater harm.en_GB
dc.description.sponsorshipMedical Research Councilen_GB
dc.identifier.citationJAMA Internal Medicine, 2014, vol. 174, issue 1, pp. 32 - 39en_GB
dc.identifier.doi10.1001/jamainternmed.2013.11312
dc.identifier.urihttp://hdl.handle.net/10871/15363
dc.language.isoenen_GB
dc.publisherAmerican Medical Associationen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/24100714en_GB
dc.rights.embargoreasonPublisher's policyen_GB
dc.rightsCopyright 2014 American Medical Associationen_GB
dc.subjectAgeden_GB
dc.subjectCohort Studiesen_GB
dc.subjectDrug Therapyen_GB
dc.subjectFemaleen_GB
dc.subjectGreat Britainen_GB
dc.subjectHumansen_GB
dc.subjectHypothyroidismen_GB
dc.subjectMaleen_GB
dc.subjectMiddle Ageden_GB
dc.subjectOdds Ratioen_GB
dc.subjectRetrospective Studiesen_GB
dc.subjectRisk Assessmenten_GB
dc.subjectThyrotropinen_GB
dc.subjectThyroxineen_GB
dc.subjectTreatment Outcomeen_GB
dc.titleFalling threshold for treatment of borderline elevated thyrotropin levels-balancing benefits and risks: evidence from a large community-based studyen_GB
dc.typeArticleen_GB
dc.date.available2015-01-01T04:00:08Z
dc.identifier.issn2168-6106
exeter.place-of-publicationUnited States
dc.descriptionThis is the author's post-print version of the article, which has been published in final form in JAMA Internal Medicine, and can be accessed via the DOI in this record.en_GB
dc.identifier.journalJAMA Internal Medicineen_GB


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