dc.contributor.author | Steele, AM | |
dc.contributor.author | Shields, BM | |
dc.contributor.author | Wensley, KJ | |
dc.contributor.author | Colclough, K | |
dc.contributor.author | Ellard, Sian | |
dc.contributor.author | Hattersley, Andrew T. | |
dc.date.accessioned | 2014-08-26T14:00:43Z | |
dc.date.issued | 2014-01-15 | |
dc.description.abstract | Glycemic targets in diabetes have been developed to minimize complication risk. Patients with heterozygous, inactivating glucokinase (GCK) mutations have mild fasting hyperglycemia from birth, resulting in an elevated glycated hemoglobin (HbA1c) level that mimics recommended levels for type 1 and type 2 diabetes. | en_GB |
dc.description.sponsorship | Diabetes UK | en_GB |
dc.description.sponsorship | National Institute for Health Research (NIHR) | en_GB |
dc.description.sponsorship | European Community’s Seventh Framework Programme | en_GB |
dc.description.sponsorship | Wellcome Trust | en_GB |
dc.identifier.citation | JAMA, 2014, Vol. 311, Issue 3, pp. 279 - 286 | en_GB |
dc.identifier.doi | 10.1001/jama.2013.283980 | |
dc.identifier.grantnumber | BDA:RD07/0003473 | en_GB |
dc.identifier.grantnumber | CEED3 223211 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/15378 | |
dc.language.iso | en | en_GB |
dc.publisher | American Medical Association | en_GB |
dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/24430320 | en_GB |
dc.rights | Copyright 2014 American Medical Association | en_GB |
dc.subject | Adult | en_GB |
dc.subject | Case-Control Studies | en_GB |
dc.subject | Cross-Sectional Studies | en_GB |
dc.subject | Diabetes Complications | en_GB |
dc.subject | Diabetes Mellitus, Type 2 | en_GB |
dc.subject | Female | en_GB |
dc.subject | Glucokinase | en_GB |
dc.subject | Hemoglobin A, Glycosylated | en_GB |
dc.subject | Humans | en_GB |
dc.subject | Hyperglycemia | en_GB |
dc.subject | Male | en_GB |
dc.subject | Middle Aged | en_GB |
dc.subject | Mutation | en_GB |
dc.subject | Prevalence | en_GB |
dc.subject | Severity of Illness Index | en_GB |
dc.subject | Time Factors | en_GB |
dc.title | Prevalence of vascular complications among patients with glucokinase mutations and prolonged, mild hyperglycemia | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2014-08-26T14:00:43Z | |
dc.identifier.issn | 0098-7484 | |
exeter.place-of-publication | United States | |
dc.description | This is the author’s version of a work that was accepted for publication in JAMA. Please cite the published version which can be accessed via the DOI in this record. | en_GB |
dc.identifier.journal | Journal of the Americal Medical Association (JAMA) | en_GB |