dc.contributor.author | Willcocks, RJ | |
dc.contributor.author | Fulford, J | |
dc.contributor.author | Barker, AR | |
dc.contributor.author | Armstrong, N | |
dc.contributor.author | Williams, CA | |
dc.date.accessioned | 2015-04-30T10:56:05Z | |
dc.date.issued | 2014-05 | |
dc.description.abstract | The phosphocreatine (PCr) recovery time constant (τ) following exercise provides a measure of mitochondrial oxidative capacity. The purpose of this investigation was to use 2 different protocols to determine τ in adolescent females. 31P-MR spectra were collected during 2 exercise tests in 6 adolescent girls (13.8 ± 0.3 y) and 7 women (23.2 ± 3.4 y). The first test consisted of 23 repeated 4 seconds maximal isometric calf contractions separated by 12-second recovery; PCr recovery between the final 18 contractions was used to calculate τ. The second test was a sustained 20-second maximal contraction; recovery was fitted with an exponential function to measure τ. PCr τ did not significantly differ between groups: (gated exercise: 4 girls: 16 ± 5 s, 7 women: 17 ± 5 s, p; sustained exercise: 6 girls: 19 ± 6 s, 7 women: 19 ± 4 s). Bland-Altman analysis demonstrated a close agreement between sustained and gated exercise. Both gated and sustained exercise appear feasible in a pediatric population, and offer a noninvasive evaluation of mitochondrial oxidative capacity. | en_GB |
dc.identifier.citation | Pediatric Exercise Science, 2014, Vol. 26 (2) pp. 210 - 217 | en_GB |
dc.identifier.doi | 10.1123/pes.2013-0043 | |
dc.identifier.uri | http://hdl.handle.net/10871/17076 | |
dc.language.iso | en | en_GB |
dc.publisher | Human Kinetics | en_GB |
dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/24893379 | en_GB |
dc.rights | © 2014 Human Kinetics, Inc. | en_GB |
dc.subject | Adolescent | en_GB |
dc.subject | Adult | en_GB |
dc.subject | Exercise | en_GB |
dc.subject | Exercise Test | en_GB |
dc.subject | Feasibility Studies | en_GB |
dc.subject | Female | en_GB |
dc.subject | Humans | en_GB |
dc.subject | Isometric Contraction | en_GB |
dc.subject | Magnetic Resonance Spectroscopy | en_GB |
dc.subject | Mitochondria | en_GB |
dc.subject | Muscle, Skeletal | en_GB |
dc.subject | Oxidation-Reduction | en_GB |
dc.subject | Time Factors | en_GB |
dc.subject | Young Adult | en_GB |
dc.title | Two protocols to measure mitochondrial capacity in women and adolescent girls: a 31P-MRS preliminary study. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2015-04-30T10:56:05Z | |
dc.identifier.issn | 0899-8493 | |
exeter.place-of-publication | United States | |
dc.description | Clinical Trial | en_GB |
dc.description | Comparative Study | en_GB |
dc.description | Journal Article | en_GB |
dc.description | As accepted for publication | en_GB |
dc.identifier.journal | Pediatric Exercise Science | en_GB |