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dc.contributor.authorBlakemore, A
dc.contributor.authorDickens, Chris
dc.contributor.authorAnderson, R
dc.contributor.authorTomenson, B
dc.contributor.authorWoodcock, A
dc.contributor.authorGuthrie, E
dc.date.accessioned2016-02-22T15:27:37Z
dc.date.issued2015-02
dc.description.abstractINTRODUCTION: Asthma accounts for considerable healthcare expenditure, a large proportion of which is attributable to use of expensive urgent healthcare. This review examines the characteristics of complex interventions that reduce urgent healthcare use in adults with asthma. METHOD: Electronic searches of MEDLINE, EMBASE, PSYCINFO, CINAHL, the British Nursing Library and the Cochrane library, from inception to January 2013 were conducted. Studies were eligible for inclusion if they: i) included adults with asthma ii) assessed the efficacy of a complex intervention using randomised controlled trial design, and iii) included a measure of urgent healthcare utilisation at follow-up. Data on participants recruited, methods, characteristics of complex interventions and the effects of the intervention on urgent healthcare use were extracted. RESULTS: 33 independent studies were identified resulting in 39 comparisons altogether. Pooled effects indicated that interventions were associated with a reduction in urgent healthcare use (OR = 0.79, 95% CI = 0.67, 0.94). When study effects were grouped according to the components of the interventions used, significant effects were seen for interventions that included general education (OR = 0.77, 95% CI = 0.64, 0.91), skills training (OR = 0.64, 95% CI = 0.48, 0.86) and relapse prevention (OR = 0.75, 95% CI = 0.57, 0.98). In multivariate meta-regression analysis, only skills training remained significant. CONCLUSIONS: Complex interventions reduced the use of urgent healthcare in adults with asthma by 21%. Those complex interventions including skills training, education and relapse prevention may be particularly effective in reducing the use of urgent healthcare in adults with asthma.en_GB
dc.description.sponsorshipNational Institute for Health Research (NIHR)en_GB
dc.identifier.citationVol. 109, pp. 147 - 156en_GB
dc.identifier.doi10.1016/j.rmed.2014.11.002
dc.identifier.grantnumberRP-PG-0707-10162en_GB
dc.identifier.otherS0954-6111(14)00390-4
dc.identifier.urihttp://hdl.handle.net/10871/20050
dc.language.isoenen_GB
dc.publisherElsevieren_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/25433953en_GB
dc.rights© 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons. org/licenses/by/3.0/).en_GB
dc.subjectAsthmaen_GB
dc.subjectComplex interventionsen_GB
dc.subjectLong-term conditionsen_GB
dc.subjectUrgent healthcareen_GB
dc.subjectAdulten_GB
dc.subjectAmbulatory Careen_GB
dc.subjectAsthmaen_GB
dc.subjectEmergency Medical Servicesen_GB
dc.subjectFemaleen_GB
dc.subjectHospitalizationen_GB
dc.subjectHumansen_GB
dc.subjectMaleen_GB
dc.titleComplex interventions reduce use of urgent healthcare in adults with asthma: systematic review with meta-regression.en_GB
dc.typeArticleen_GB
dc.date.available2016-02-22T15:27:37Z
exeter.place-of-publicationEngland
dc.descriptionOpen access article.en_GB
dc.identifier.journalRespiratory Medicineen_GB
dc.identifier.pmid25433953


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