How useful is thrombocytosis in predicting an underlying cancer in primary care? Systematic review protocol
University of Exeter
Early diagnosis of cancer is imperative to reduce the cancer burden in the UK and improve cancer survival. Identifying early markers of cancer can help general practitioners to direct patients at the greatest risk of cancer to appropriate investigative services. A raised platelet count, or thrombocytosis, has been linked to malignancy and identified as a marker of poor prognosis in secondary care, but there is little evidence around the importance of this marker in a primary care setting, within a diagnostic context. This review aims to identify and explore the body of evidence concerning the association between thrombocytosis and cancer in primary care. This protocol was produced using guidance from the PRISMA-P statement.