Show simple item record

dc.contributor.authorHamilton, W
dc.contributor.authorStapley, Sally
dc.contributor.authorCampbell, C
dc.contributor.authorLyratzopoulos, G
dc.contributor.authorRubin, Greg
dc.contributor.authorNeal, Richard D.
dc.date.accessioned2016-05-03T13:56:38Z
dc.date.issued2015
dc.description.abstractBACKGROUND: This study aimed to answer the question 'for which cancers, in a symptomatic patient, does expediting the diagnosis provide an improvement in mortality and/or morbidity?' METHODS: An initial ranking was constructed from previous work identifying 'avoidable deaths' for 21 common cancers in the UK. In a two-round modified Delphi exercise, 22 experts, all experienced across multiple cancers, used an evidence pack summarising recent relevant publications and their own experience to adjust this ranking. Participants also answered on a Likert scale whether they anticipated mortality or morbidity benefits for each cancer from expedited diagnosis. RESULTS: Substantial changes in ranking occurred in the Delphi exercise. Finally, expedited diagnosis was judged to provide the greatest mortality benefit in breast cancer, uterine cancer and melanoma, and least in brain and pancreatic cancers. Three cancers, prostate, brain and pancreas, attracted a median answer of 'disagree' to whether they expected mortality benefits from expedited diagnosis of symptomatic cancer. CONCLUSIONS: Our results can guide future research, with emphasis given to studying interventions to improve symptomatic diagnosis of those cancers ranked highly. In contrast, research efforts for cancers with the lowest rankings could be re-directed towards alternative avenues more likely to yield benefit, such as screening or treatment.en_GB
dc.identifier.citationVol. 15, pp. 820 -en_GB
dc.identifier.doi10.1186/s12885-015-1865-x
dc.identifier.urihttp://hdl.handle.net/10871/21352
dc.language.isoenen_GB
dc.publisherBioMed Centralen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/26514369en_GB
dc.rights© 2015 Hamilton et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en_GB
dc.titleFor which cancers might patients benefit most from expedited symptomatic diagnosis? Construction of a ranking order by a modified Delphi technique.en_GB
dc.typeArticleen_GB
dc.date.available2016-05-03T13:56:38Z
dc.identifier.issn1471-2407
exeter.place-of-publicationEngland
dc.descriptionPublished onlineen_GB
dc.descriptionJournal Articleen_GB
dc.descriptionResearch Support, Non-U.S. Gov'ten_GB
dc.identifier.journalBMC Canceren_GB


Files in this item

This item appears in the following Collection(s)

Show simple item record