dc.contributor.author | Backer, LC | |
dc.contributor.author | Kirkpatrick, B | |
dc.contributor.author | Fleming, LE | |
dc.contributor.author | Cheng, YS | |
dc.contributor.author | Pierce, R | |
dc.contributor.author | Bean, JA | |
dc.contributor.author | Clark, R | |
dc.contributor.author | Johnson, D | |
dc.contributor.author | Wanner, A | |
dc.contributor.author | Tamer, R | |
dc.contributor.author | Zhou, Y | |
dc.contributor.author | Baden, DG | |
dc.date.accessioned | 2018-01-02T10:12:18Z | |
dc.date.issued | 2005-02 | |
dc.description.abstract | Karenia brevis (formerly Gymnodinium breve) is a marine dinoflagellate responsible for red tides that form in the Gulf of Mexico. K. brevis produces brevetoxins, the potent toxins that cause neurotoxic shellfish poisoning. There is also limited information describing human health effects from environmental exposures to brevetoxins. Our objective was to examine the impact of inhaling aerosolized brevetoxins during red tide events on self-reported symptoms and pulmonary function. We recruited a group of 28 healthy lifeguards who are occupationally exposed to red tide toxins during their daily work-related activities. They performed spirometry tests and reported symptoms before and after their 8-hr shifts during a time when there was no red tide (unexposed period) and again when there was a red tide (exposed period). We also examined how mild exercise affected the reported symptoms and spirometry tests during unexposed and exposed periods with a subgroup of the same lifeguards. Environmental sampling (K. brevis cell concentrations in seawater and brevetoxin concentrations in seawater and air) was used to confirm unexposed/exposed status. Compared with unexposed periods, the group of lifeguards reported more upper respiratory symptoms during the exposed periods. We did not observe any impact of exposure to aerosolized brevetoxins, with or without mild exercise, on pulmonary function. | en_GB |
dc.description.sponsorship | This research was supported by the Centers for
Disease Control and Prevention, grant P01 ES 10594
from the National Institute of Environmental Health
Sciences, and the Florida Department of Health. | en_GB |
dc.identifier.citation | Vol. 113 (5), pp. 644 - 649 | en_GB |
dc.identifier.doi | 10.1289/ehp.7502 | |
dc.identifier.uri | http://hdl.handle.net/10871/30769 | |
dc.language.iso | en | en_GB |
dc.publisher | National Institute of Environmental Health Sciences (NIEHS) | en_GB |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pubmed/15866778 | en_GB |
dc.rights | Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, ?Reproduced with permission from Environmental Health Perspectives?); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright. | en_GB |
dc.subject | Adolescent | en_GB |
dc.subject | Adult | en_GB |
dc.subject | Animals | en_GB |
dc.subject | Dinoflagellida | en_GB |
dc.subject | Exercise | en_GB |
dc.subject | Female | en_GB |
dc.subject | Florida | en_GB |
dc.subject | Humans | en_GB |
dc.subject | Inhalation Exposure | en_GB |
dc.subject | Male | en_GB |
dc.subject | Marine Toxins | en_GB |
dc.subject | Occupational Exposure | en_GB |
dc.subject | Oxocins | en_GB |
dc.subject | Recreation | en_GB |
dc.subject | Respiratory Tract Diseases | en_GB |
dc.subject | Seawater | en_GB |
dc.subject | Swimming | en_GB |
dc.title | Occupational exposure to aerosolized brevetoxins during Florida red tide events: effects on a healthy worker population | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2018-01-02T10:12:18Z | |
dc.identifier.issn | 0091-6765 | |
exeter.place-of-publication | United States | en_GB |
dc.description | This is the final version of the article. Available from NIEHS via the DOI in this record. | en_GB |
dc.identifier.journal | Environmental Health Perspectives | en_GB |