Unloosing the Gordian knot of peroxisome formation
Current Opinion in Cell Biology
Elsevier for Current Opinion
Reason for embargo
Currently under an indefinite embargo pending publication by Elsevier. 12 month embargo to be applied on publication
Peroxisome biogenesis is governed by molecular machineries, which are either unique to peroxisomes or are partially shared with mitochondria. As peroxisomes have important protective functions in the cell, modulation of their number is important for human health and disease. Significant progress has been made towards our understanding of the mechanisms of peroxisome formation, revealing a remarkable plasticity of the peroxisome biogenesis pathway. Here we discuss most recent findings with particular focus on peroxisome formation in mammalian cells.
This work was supported by the Biotechnology and Biological Sciences Research Council (BB/K006231/1, BB/N01541X/1 to M.S.).
This is the author accepted manuscript.
Awaiting citation and DOI