The impact of eliminating age inequalities in stage at diagnosis on breast cancer survival for older women
dc.contributor.author | Rutherford, MJ | |
dc.contributor.author | Abel, GA | |
dc.contributor.author | Greenberg, DC | |
dc.contributor.author | Lambert, PC | |
dc.contributor.author | Lyratzopoulos, G | |
dc.date.accessioned | 2019-02-08T10:35:48Z | |
dc.date.issued | 2015-03-03 | |
dc.description.abstract | BACKGROUND: Older women with breast cancer have poorer relative survival outcomes, but whether achieving earlier stage at diagnosis would translate to substantial reductions in mortality is uncertain.METHODS: We analysed data on East of England women with breast cancer (2006-2010) aged 70+ years. We estimated survival for different stage-deprivation-age group strata using both the observed and a hypothetical stage distribution (assuming that all women aged 75+ years acquired the stage distribution of those aged 70-74 years). We subsequently estimated deaths that could be postponed beyond 5 years from diagnosis if women aged 75+ years had the hypothetical stage distribution. We projected findings to the English population using appropriate age and socioeconomic group weights.RESULTS: For a typically sized annual cohort in the East of England, 27 deaths in women with breast cancer aged 75+ years can be postponed within 5 years from diagnosis if their stage distribution matched that of the women aged 70-74 years (4.8% of all 566 deaths within 5 years post diagnosis in this population). Under assumptions, we estimate that the respective number for England would be 280 deaths (5.0% of all deaths within 5 years post diagnosis in this population).CONCLUSIONS: The findings support ongoing development of targeted campaigns aimed at encouraging prompt presentation in older women. | en_GB |
dc.description.sponsorship | Cancer Research UK | en_GB |
dc.description.sponsorship | Cancer Research UK | en_GB |
dc.description.sponsorship | National Institute for Health Research (NIHR) | en_GB |
dc.identifier.citation | Vol. 112, pp. S124 - S128 | en_GB |
dc.identifier.doi | 10.1038/bjc.2015.51 | |
dc.identifier.grantnumber | CRUK_A13275 | en_GB |
dc.identifier.grantnumber | A18180 | en_GB |
dc.identifier.grantnumber | NIHR PDF-2011-04-047 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/35831 | |
dc.language.iso | en | en_GB |
dc.publisher | Springer Nature | en_GB |
dc.rights | © 2015 Cancer Research UK. Thisworkislicensed under theCreativeCommons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ | en_GB |
dc.subject | avoidable deaths | en_GB |
dc.subject | age inequalities | en_GB |
dc.subject | excess mortality models | en_GB |
dc.title | The impact of eliminating age inequalities in stage at diagnosis on breast cancer survival for older women | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2019-02-08T10:35:48Z | |
dc.identifier.issn | 0007-0920 | |
dc.description | This is the final published version. Available from Springer Nature via the DOI in this record. | en_GB |
dc.identifier.journal | British journal of cancer | en_GB |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_GB |
pubs.euro-pubmed-id | MED:25734394 | |
dcterms.dateAccepted | 2015-03-03 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2015-03-03 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2019-02-08T10:33:01Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2019-02-08T10:35:51Z | |
refterms.panel | A | en_GB |
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