MbyRes Dissertations
Recent Submissions
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The Role of Seaweed Antimicrobials in Selection for Antibiotic Resistance
(University of ExeterExeter Medical School, 2018-02-12)Antibiotic resistance is quickly becoming one of the biggest modern-day threats to human health. It has not only been observed in the clinic but in natural environments as well. Selection for antimicrobial resistant bacteria ... -
An investigation of mining impacts on bats in South-West England
(University of ExeterCollege of Life and Environmental Sciences, 2018-03-23)The extraction of minerals through open-pit mining can result in sudden and extensive land use change, often posing threats to local biodiversity. Bats are particularly vulnerable to the impacts of mining, but their ... -
Cloning and functional analysis of a Rice NLR Immune receptor pair- RPR (Rice Paired Receptor) 1&2
(University of ExeterCollege of life and environmental Sciences, 2018-01-10)The intracellular nucleotide-binding leucine-rich repeat (NLR) immune receptors of plants often work in pairs to percieve pathogen effectors and innitiate immunity reponses. In this article, we focused on gene cloning and ... -
Older patients with odontoid process and cervical spine fractures: evaluating clinical risk factors, clinical pathways and treatment to prevent further fracture.
(University of ExeterCollege of Medicine and Health, 2018-07-26)INTRODUCTION The most common site of cervical spine fracture in the elderly is the odontoid process. These fractures result predominantly from ground level falls. Osteoporosis has been identified as an important predisposing ... -
Clinical implications of persistent beta cell function in long duration type 1 diabetes
(University of ExeterUniversity of Exeter Medical School, 2018-08-15)Type 1 diabetes was thought to be a disease of absolute insulin deficiency. However, recent evidence has shown that most people with Type 1 diabetes have persistent endogenous insulin production, even those with long disease ... -
The effect of diet and physical activity on quality of life, wellbeing and treatment satisfaction, in newly diagnosed Type 2 diabetes
(University of ExeterUniversity of Exeter Medical School, 2018-08-02)Type 2 diabetes impacts upon quality of life. Quality of life is lower in diabetes than in the general population but what happens to quality of life over the first years following the diagnosis is less clear. In addition, ... -
DNA Methylation in Rectal Cancer: Validating Findings of an Epigenome-Wide Association Study
(University of ExeterComplex Disease Epigenetics Group, Exeter Medical SchoolExeter Surgical Health Service Research Unit, Royal Devon and Exeter NHS Foundation Trust, 2018-05-29)Background: Preliminary studies conducted by our group utilised the Illumina Infinium Human Methylation 450k Beadchip array to perform an epigenome-wide association study (EWAS) of 15 matched rectal tumour (RT) and adjacent ... -
Developing a Stratified Approach to Treatment in Type 2 Diabetes
(University of ExeterMedical Sciences, 2018-08-01)Type 2 diabetes (T2D) is a leading cause of global morbidity and mortality characterised by deficits in insulin secretion and function. Diabetes’ poor health outcomes are largely attributed to its macrovascular and ... -
Investigation of the Molecular Basis of Primary Ciliary Dyskinesia and Situs Inversus amongst the Amish
(University of ExeterMedical School, 2018-07-31)Cilia are hair-like projections from eukaryotic cells: they are complex organelles that can be split into motile (normal/embryonic nodal) and non-motile types. Primary ciliary dyskinesia (PCD) is genetically heterogeneous, ... -
People Protecting Place: Anti-Fracking Campaigns in the United Kingdom
(University of ExeterPolitics, 2018-07-03)This study is concerned with the anti-fracking campaigns that have emerged in the UK in recent years, and on which only a limited social science literature has been developed. Specifically, this thesis is guided by a ... -
Remote Camera Technology and its Role in Grey Seal Haul-out Assessment
(University of ExeterCollege of Life and Environmental Science, 2018-03-05)Remote cameras can permit non-invasive monitoring of marine species and habitats. Using automated time-lapse cameras in combination with human observations and an infrared visitor counter, this project collected data on ... -
Testing of a Valsalva Assist Device (VAD) to assess effects on heart rate and strain pressures achieved compared to a standard manometer in healthy volunteers performing standard and modified Valsalva manoeuvres.
(University of ExeterEmergency Department, Exeter Medical School, 2018-06-29)Background Supraventricular tachycardia (SVT) is a relatively common condition causing palpitations, which, if not treated, can have serious adverse effects. SVT can initially be treated with a Valsalva manoeuvre (VM) ... -
The impacts of out-group threats on within- and between-group behaviours in the cooperatively breeding white-browed sparrow-weaver
(University of ExeterBiosciences, 2018-02-05)Groups face a variety of potential threats from out-group conspecifics. Individuals from outside the group may challenge the breeding position and success of group members and groups often defend against neighbouring or ... -
Investigating the role of NADPH oxidases during infection related development of the rice blast fungus Magnaporthe oryzae
(University of ExeterBiosciences, 2018-01-08)Rice blast disease is a major threat to global food security, destroying 30% of annual rice crops globally, and with disease remaining difficult to control. The causal agent of rice blast, Magnaporthe oryzae infects plants ... -
The significance of fine-scale climate for plants
(University of ExeterCLES Biosciences, 2018-03-05)Abstract 1. Global climate change will be one of the biggest threats to biodiversity over the course of this century. 21st century biodiversity conservation thus depends much on our ability help species adapt. A better ... -
DNA Methylation in Rectal Cancer
(University of ExeterUniversity of Exeter Medical School, 2018-08-09)Rectal cancer differs from colon cancer in terms of its underlying biological behaviour, clinical course, genetic and epigenetic aetiology. Epigenetic mechanisms modify gene expression independently of DNA sequence. DNA ... -
Investigating the geochemistry and microbial ecology of heap bioleaching systems at the agglomerate scale
(University of ExeterCamborne School of Mines, 2018-03-10)Heap bioleaching is an alternative processing method for low-grade copper ores. Microbial iron oxidation produces ferric iron which solubilises copper-bearing minerals while microbially generated acid maintains a pH ... -
Do maternal effects influence phenotypic traits in a cooperatively breeding mammal?
(University of ExeterBiosciences, 2018-03-09)Animals within populations show considerable variation in physiological and behavioural traits. These phenotypic differences can be profoundly influenced by the ecological and social conditions experienced in early life. ... -
Optimisation of transition metal dichalcogenide devices for measurement of spin-Hall voltages generated by optical spin orientation
(University of ExeterPhysics, 2018-01-02)Here we propose a design to optimise measurement of the transverse spin voltage resulting from the spin Hall effect (SHE) generated by shining circularly polarised light on a transition metal dichalcogenide (TMD) monolayer. ... -
The evolution and protective benefits of immune responses in North American house finches (Haemorhous mexicanus) to Mycoplasma gallisepticum
(University of ExeterBiosciences, 2018-05-10)Pathogen spillover to novel hosts represents a huge selective event, and can result in rapid evolutionary changes in both the pathogen and the host. However, it is seldom possible to identify which specific host characteristics ...