The study of socioethical issues in systems biology

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The study of socioethical issues in systems biology

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Title: The study of socioethical issues in systems biology
Author: O'Malley, Maureen A.
Calvert, Jane
Dupré, John
Citation: 7(4), pp.67-78
Publisher: Taylor & Francis
Journal: American Journal of Bioethics
Date Issued: 2007-04
URI: http://hdl.handle.net/10036/47820
Links: http://www.bioethics.net/journal/index.php?jid=32
Abstract: Systems biology is the rapidly growing and heavily funded successor science to genomics. Its mission is to integrate extensive bodies of molecular data into a detailed mathematical understanding of all life processes, with an ultimate view to their prediction and control. Despite its high profile and widespread practice, there has so far been almost no bioethical attention paid to systems biology and its potential social consequences. We outline some of systems biology's most important socioethical issues by contrasting the concept of systems as dynamic processes against the common static interpretation of genomes. New issues arise around systems biology's capacities for in silico testing, changing cultural understandings of life, synthetic biology, and commercialization. We advocate an interdisciplinary and interactive approach that integrates social and philosophical analysis and engages closely with the science. Overall, we argue that systems biology socioethics could stimulate new ways of thinking about socioethical studies of life sciences.
Type: Article
Keywords: systems biologygenomicsbioethicssocioethicslife sciencesELSIgenetics
ISSN: 1526-5161
Funders/Sponsor: ESRC; AHRC


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