Random access parallel microscopy
dc.contributor.author | Ashraf, M | |
dc.contributor.author | Sharika, M | |
dc.contributor.author | Sim, BR | |
dc.contributor.author | Tam, A | |
dc.contributor.author | Rahemipour, K | |
dc.contributor.author | Brousseau, D | |
dc.contributor.author | Thibault, S | |
dc.contributor.author | Corbett, AD | |
dc.contributor.author | Bub, G | |
dc.date.accessioned | 2021-01-13T09:38:41Z | |
dc.date.issued | 2021-01-12 | |
dc.description.abstract | We introduce a random access parallel (RAP) imaging modality that uses a novel design inspired by a Newtonian telescope to image multiple spatially separated samples without moving parts or robotics. This scheme enables near simultaneous image capture of multiple petri dishes and random-access imaging with sub-millisecond switching times at the full resolution of the camera. This enables the RAP system to capture long duration records from different samples in parallel, which is not possible using conventional automated microscopes. The system is demonstrated by continuously imaging multiple cardiac monolayer and Caenorhabditis elegans (C. elegans) preparations. | en_GB |
dc.description.sponsorship | National Science and Engineering Research Council of Canada | en_GB |
dc.identifier.citation | Vol. 10, article e56426 | en_GB |
dc.identifier.doi | 10.7554/elife.56426 | |
dc.identifier.grantnumber | RGPIN-2018-05346 | en_GB |
dc.identifier.grantnumber | RGPIN-2016-05962 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/124381 | |
dc.language.iso | en | en_GB |
dc.publisher | eLife Sciences Publication | en_GB |
dc.rights | © 2021, Ashraf et al. This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited. | en_GB |
dc.title | Random access parallel microscopy | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2021-01-13T09:38:41Z | |
dc.description | This is the author accepted manuscript. the final version is available from eLife Sciences Publications via the DOI in this record | en_GB |
dc.identifier.eissn | 2050-084X | |
dc.identifier.journal | eLife | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2021-01-11 | |
exeter.funder | ::Engineering and Physical Sciences Research Council (EPSRC) | en_GB |
rioxxterms.version | AM | en_GB |
rioxxterms.licenseref.startdate | 2021-01-12 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2021-01-13T09:36:44Z | |
refterms.versionFCD | AM | |
refterms.dateFOA | 2021-01-13T09:38:45Z | |
refterms.panel | B | en_GB |
Files in this item
This item appears in the following Collection(s)
Except where otherwise noted, this item's licence is described as © 2021, Ashraf et al.
This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.