Control of Helical Navigation by Three-Dimensional Flagellar Beating
dc.contributor.author | Cortese, D | |
dc.contributor.author | Wan, KY | |
dc.date.accessioned | 2021-02-26T12:22:16Z | |
dc.date.issued | 2021-02-24 | |
dc.description.abstract | Helical swimming is a ubiquitous strategy for motile cells to generate self-gradients for environmental sensing. The model biflagellate Chlamydomonas reinhardtii rotates at a constant 1–2 Hz as it swims, but the mechanism is unclear. Here, we show unequivocally that the rolling motion derives from a persistent, nonplanar flagellar beat pattern. This is revealed by high-speed imaging and micromanipulation of live cells. We construct a fully 3D model to relate flagellar beating directly to the free-swimming trajectories. For realistic geometries, the model reproduces both the sense and magnitude of the axial rotation of live cells. We show that helical swimming requires further symmetry breaking between the two flagella. These functional differences underlie all tactic responses, particularly phototaxis. We propose a control strategy by which cells steer toward or away from light by modulating the sign of biflagellar dominance. | en_GB |
dc.description.sponsorship | European Union Horizon 2020 | en_GB |
dc.description.sponsorship | Academy of Medical Sciences and Global Challenges Research Fund | en_GB |
dc.identifier.citation | Vol. 126 (8), article 088003 | en_GB |
dc.identifier.doi | 10.1103/physrevlett.126.088003 | |
dc.identifier.grantnumber | 853560 | en_GB |
dc.identifier.grantnumber | SBF003\1160 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/124933 | |
dc.language.iso | en | en_GB |
dc.publisher | American Physical Society (APS) | en_GB |
dc.rights | © 2021. Open access. Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. | en_GB |
dc.title | Control of Helical Navigation by Three-Dimensional Flagellar Beating | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2021-02-26T12:22:16Z | |
dc.identifier.issn | 0031-9007 | |
exeter.article-number | 088003 | en_GB |
dc.description | This is the final version. Available on open access from the American Physical Society via the DOI in this record | en_GB |
dc.identifier.journal | Physical Review Letters | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2021-01-13 | |
exeter.funder | ::Academy of Medical Sciences | en_GB |
exeter.funder | ::European Commission | en_GB |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2021-02-24 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2021-02-26T12:18:41Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2021-02-26T12:22:20Z | |
refterms.panel | B | en_GB |
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Except where otherwise noted, this item's licence is described as © 2021. Open access. Published by the American Physical Society under the terms of
the Creative Commons Attribution 4.0 International license.
Further distribution of this work must maintain attribution to
the author(s) and the published article’s title, journal citation,
and DOI.