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Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

dc.contributor.authorVimaleswaran, KS
dc.contributor.authorBerry, DJ
dc.contributor.authorLu, C
dc.contributor.authorTikkanen, E
dc.contributor.authorPilz, S
dc.contributor.authorHiraki, LT
dc.contributor.authorCooper, JD
dc.contributor.authorDastani, Z
dc.contributor.authorLi, R
dc.contributor.authorHouston, DK
dc.contributor.authorWood, Andrew R.
dc.contributor.authorMichaëlsson, K
dc.contributor.authorVandenput, L
dc.contributor.authorZgaga, L
dc.contributor.authorYerges-Armstrong, LM
dc.contributor.authorMcCarthy, MI
dc.contributor.authorDupuis, J
dc.contributor.authorKaakinen, M
dc.contributor.authorKleber, ME
dc.contributor.authorJameson, K
dc.contributor.authorArden, N
dc.contributor.authorRaitakari, O
dc.contributor.authorViikari, J
dc.contributor.authorLohman, KK
dc.contributor.authorFerrucci, L
dc.contributor.authorMelhus, H
dc.contributor.authorIngelsson, E
dc.contributor.authorByberg, L
dc.contributor.authorLind, L
dc.contributor.authorLorentzon, M
dc.contributor.authorSalomaa, V
dc.contributor.authorCampbell, H
dc.contributor.authorDunlop, Malcolm
dc.contributor.authorMitchell, BD
dc.contributor.authorHerzig, KH
dc.contributor.authorPouta, A
dc.contributor.authorHartikainen, AL
dc.contributor.authorGenetic Investigation of Anthropometric Traits-GIANT Consortium
dc.contributor.authorStreeten, EA
dc.contributor.authorTheodoratou, E
dc.contributor.authorJula, A
dc.contributor.authorWareham, NJ
dc.contributor.authorOhlsson, C
dc.contributor.authorFrayling, Timothy M.
dc.contributor.authorKritchevsky, SB
dc.contributor.authorSpector, TD
dc.contributor.authorRichards, JB
dc.contributor.authorLehtimäki, T
dc.contributor.authorOuwehand, WH
dc.contributor.authorKraft, P
dc.contributor.authorCooper, Cyrus
dc.contributor.authorMärz, W
dc.contributor.authorPower, C
dc.contributor.authorLoos, RJ
dc.contributor.authorWang, TJ
dc.contributor.authorJärvelin, MR
dc.contributor.authorWhittaker, JC
dc.contributor.authorHingorani, Aroon
dc.contributor.authorHyppönen, E
dc.date.accessioned2013-12-09T14:06:32Z
dc.date.issued2013-02-05
dc.description.abstractObesity is associated with vitamin D deficiency, and both are areas of active public health concern. We explored the causality and direction of the relationship between body mass index (BMI) and 25-hydroxyvitamin D [25(OH)D] using genetic markers as instrumental variables (IVs) in bi-directional Mendelian randomization (MR) analysis.en_GB
dc.identifier.citationVol. 10, Issue 2, article e1001383en_GB
dc.identifier.doi10.1371/journal.pmed.1001383
dc.identifier.urihttp://hdl.handle.net/10871/14216
dc.language.isoenen_GB
dc.publisherPublic Library of Scienceen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/23393431en_GB
dc.titleCausal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohortsen_GB
dc.typeArticleen_GB
dc.date.available2013-12-09T14:06:32Z
dc.identifier.issn1549-1277
exeter.place-of-publicationUnited States
dc.descriptionThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_GB
dc.identifier.journalPLoS Medicineen_GB


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