Genomics and successful aging: grounds for renewed optimism?

Pilling, LC; Harries, LW; Powell, J; et al.Llewellyn, DJ; Ferrucci, L; Melzer, D
Date: 1 May 2012
Journal
The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
Publisher
Oxford University Press
Publisher DOI
https://doi.org/10.1093/gerona/gls091
Related links
http://www.ncbi.nlm.nih.gov/pubmed/22454374
Abstract
Successful aging depends in part on delaying age-related disease onsets until later in life. Conditions including coronary artery disease, Alzheimer's disease, prostate cancer, and type 2 diabetes are moderately heritable. Genome-wide association studies have identified many risk associated single-nucleotide polymorphisms for these ...
Successful aging depends in part on delaying age-related disease onsets until later in life. Conditions including coronary artery disease, Alzheimer's disease, prostate cancer, and type 2 diabetes are moderately heritable. Genome-wide association studies have identified many risk associated single-nucleotide polymorphisms for these conditions, but much heritability remains unaccounted for. Nevertheless, a great deal is being learned.
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