New genetic loci link adipose and insulin biology to body fat distribution

Shungin, D; Winkler, TW; Croteau-Chonka, DC; Ferreira, T; Locke, AE; Mägi, R; Strawbridge, RJ; Pers, TH; Fischer, Krista; Justice, AE; Workalemahu, T; Wu, JM; Buchkovich, ML; Heard-Costa, NL; Roman, TS; Drong, AW; Song, C; Gustafsson, S; Day, Felix R.; Esko, T; Fall, T; Kutalik, Z; Luan, J; Randall, JC; Scherag, A; Vedantam, S; Wood, Andrew R.; Chen, J; Fehrmann, R; Karjalainen, J; Kahali, B; Liu, CT; Schmidt, EM; Absher, D; Amin, N; Anderson, D; Beekman, M; Bragg-Gresham, JL; Buyske, S; Demirkan, A; Ehret, GB; Feitosa, MF; Goel, A; Jackson, AU; Johnson, T; Kleber, ME; Kristiansson, K; Mangino, M; Mateo Leach, I; Medina-Gomez, C; Palmer, CD; Pasko, Dorota; Pechlivanis, S; Peters, MJ; Prokopenko, I; Stančáková, A; Ju Sung, Y; Tanaka, T; Teumer, A; Van Vliet-Ostaptchouk, JV; Yengo, L; Zhang, W; Albrecht, E; Ärnlöv, J; Arscott, GM; Bandinelli, S; Barrett, A; Bellis, C; Bennett, AJ; Berne, C; Blüher, M; Böhringer, S; Bonnet, F; Böttcher, Y; Bruinenberg, M; Carba, DB; Caspersen, IH; Clarke, R; Daw, EW; Deelen, J; Deelman, E; Delgado, G; Doney, AS; Eklund, N; Erdos, MR; Estrada, K; Eury, E; Friedrich, N; Garcia, ME; Giedraitis, V; Gigante, B; Go, AS; Golay, A; Grallert, H; Grammer, TB; Gräßler, J; Grewal, J; Groves, Christopher J.; Haller, T; Hallmans, G; Hartman, CA; Hassinen, M; Hayward, C; Heikkilä, K; Herzig, KH; Helmer, Q; Hillege, Hans; Holmen, O; Hunt, SC; Isaacs, A; Ittermann, T; James, AL; Johansson, I; Juliusdottir, T; Kalafati, IP; Kinnunen, L; Koenig, W; Kooner, IK; Kratzer, W; Lamina, C; Leander, K; Lee, NR; Lichtner, P; Lind, L; Lindström, J; Lobbens, S; Lorentzon, M; Mach, F; Magnusson, PK; Mahajan, A; McArdle, WL; Menni, C; Merger, S; Mihailov, E; Milani, L; Mills, R; Moayyeri, A; Monda, KL; Mooijaart, SP; Mühleisen, TW; Mulas, A; Müller, G; Müller-Nurasyid, M; Nagaraja, R; Nalls, MA; Narisu, N; Glorioso, N; Nolte, IM; Olden, M; Rayner, NW; Renstrom, F; Ried, JS; Robertson, NR; Rose, LM; Sanna, S; Scharnagl, H; Scholtens, S; Sennblad, B; Seufferlein, T; Sitlani, CM; Vernon Smith, A; Stirrups, K; Stringham, HM; Sundström, J; Swertz, MA; Swift, AJ; Syvänen, AC; Tayo, BO; Thorand, B; Thorleifsson, G; Tomaschitz, A; Troffa, C; van Oort, FV; Verweij, N; Vonk, JM; Waite, LL; Wennauer, R; Wilsgaard, T; Wojczynski, MK; Wong, A; Zhang, Q; Hua Zhao, J; Brennan, EP; Choi, M; Eriksson, P; Folkersen, L; Franco-Cereceda, A; Gharavi, AG; Hedman, ÅK; Hivert, MF; Huang, J; Kanoni, S; Karpe, F; Keildson, S; Kiryluk, K; Liang, L; Lifton, RP; Ma, B; McKnight, AJ; McPherson, R; Metspalu, A; Min, JL; Moffatt, MF; Montgomery, GW; Murabito, JM; Nicholson, G; Nyholt, DR; Olsson, C; Perry, John R.B.; Reinmaa, E; Salem, RM; Sandholm, N; Schadt, EE; Scott, RA; Stolk, L; Vallejo, EE; Westra, HJ; Zondervan, KT; ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium; Amouyel, P; Arveiler, D; Bakker, SJ; Beilby, J; Bergman, RN; Blangero, J; Brown, MJ; Burnier, M; Campbell, H; Chakravarti, A; Chines, PS; Claudi-Boehm, S; Collins, FS; Crawford, DC; Danesh, J; de Faire, U; de Geus, Eco; Dörr, M; Erbel, R; Eriksson, Johan G.; Farrall, M; Ferrannini, E; Ferrières, J; Forouhi, NG; Forrester, T; Franco, OH; Gansevoort, RT; Gieger, C; Gudnason, V; Haiman, CA; Harris, Tamara; Hattersley, Andrew T.; Heliövaara, M; Hicks, AA; Hingorani, Aroon; Hoffmann, W; Hofman, A; Homuth, G; Humphries, SE; Hyppönen, E; Illig, T; Jarvelin, MR; Johansen, B; Jousilahti, P; Jula, AM; Kaprio, J; Kee, F; Keinanen-Kiukaanniemi, SM; Kooner, JS; Kooperberg, C; Kovacs, P; Kraja, AT; Kumari, M; Kuulasmaa, K; Kuusisto, J; Lakka, TA; Langenberg, C; Le Marchand, L; Lehtimäki, T; Lyssenko, V; Männistö, S; Marette, A; Matise, TC; McKenzie, CA; McKnight, B; Musk, AW; Möhlenkamp, S; Morris, AD; Nelis, M; Ohlsson, C; Oldehinkel, AJ; Ong, KK; Palmer, LJ; Penninx, BW; Peters, A; Pramstaller, PP; Raitakari, OT; Rankinen, T; Rao, DC; Rice, TK; Ridker, PM; Ritchie, MD; Rudan, I; Salomaa, V; Samani, NJ; Saramies, J; Sarzynski, MA; Schwarz, PE; Shuldiner, AR; Staessen, JA; Steinthorsdottir, V; Stolk, RP; Strauch, K; Tönjes, A; Tremblay, A; Tremoli, E; Vohl, MC; Völker, U; Vollenweider, P; Wilson, JF; Witteman, JC; Adair, LS; Bochud, M; Boehm, BO; Bornstein, SR; Bouchard, C; Cauchi, S; Caulfield, MJ; Chambers, JC; Chasman, DI; Cooper, RS; Dedoussis, George V.; Ferrucci, L; Froguel, P; Grabe, HJ; Hamsten, A; Hui, J; Hveem, K; Jöckel, KH; Kivimaki, M; Kuh, D; Laakso, M; Liu, Y; März, W; Munroe, PB; Njølstad, I; Oostra, BA; Palmer, CN; Pedersen, NL; Perola, M; Pérusse, L; Peters, U; Power, C; Quertermous, T; Rauramaa, R; Rivadeneira, F; Saaristo, TE; Saleheen, D; Sinisalo, J; Slagboom, PE; Snieder, H; Spector, TD; Thorsteinsdottir, U; Stumvoll, M; Tuomilehto, J; Uitterlinden, AG; Uusitupa, M; van der Harst, P; Veronesi, G; Walker, M; Wareham, NJ; Watkins, H; Wichmann, HE; Abecasis, GR; Assimes, TL; Berndt, SI; Boehnke, M; Borecki, IB; Deloukas, P; Franke, L; Frayling, Timothy M.; Groop, Leif; Hunter, DJ; Kaplan, RC; O'Connell, JR; Qi, L; Schlessinger, D; Strachan, DP; Stefansson, K; van Duijn, CM; Willer, CJ; Visscher, PM; Yang, J; Hirschhorn, JN; Zillikens, MC; McCarthy, MI; Speliotes, EK; North, KE; Fox, CS; Barroso, I; Franks, PW; Ingelsson, E; Heid, IM; Loos, RJ; Cupples, LA; Morris, AP; Lindgren, CM; Mohlke, KL

Shungin, D; Winkler, TW; Croteau-Chonka, DC; et al.Ferreira, T; Locke, AE; Mägi, R; Strawbridge, RJ; Pers, TH; Fischer, Krista; Justice, AE; Workalemahu, T; Wu, JM; Buchkovich, ML; Heard-Costa, NL; Roman, TS; Drong, AW; Song, C; Gustafsson, S; Day, Felix R.; Esko, T; Fall, T; Kutalik, Z; Luan, J; Randall, JC; Scherag, A; Vedantam, S; Wood, Andrew R.; Chen, J; Fehrmann, R; Karjalainen, J; Kahali, B; Liu, CT; Schmidt, EM; Absher, D; Amin, N; Anderson, D; Beekman, M; Bragg-Gresham, JL; Buyske, S; Demirkan, A; Ehret, GB; Feitosa, MF; Goel, A; Jackson, AU; Johnson, T; Kleber, ME; Kristiansson, K; Mangino, M; Mateo Leach, I; Medina-Gomez, C; Palmer, CD; Pasko, Dorota; Pechlivanis, S; Peters, MJ; Prokopenko, I; Stančáková, A; Ju Sung, Y; Tanaka, T; Teumer, A; Van Vliet-Ostaptchouk, JV; Yengo, L; Zhang, W; Albrecht, E; Ärnlöv, J; Arscott, GM; Bandinelli, S; Barrett, A; Bellis, C; Bennett, AJ; Berne, C; Blüher, M; Böhringer, S; Bonnet, F; Böttcher, Y; Bruinenberg, M; Carba, DB; Caspersen, IH; Clarke, R; Daw, EW; Deelen, J; Deelman, E; Delgado, G; Doney, AS; Eklund, N; Erdos, MR; Estrada, K; Eury, E; Friedrich, N; Garcia, ME; Giedraitis, V; Gigante, B; Go, AS; Golay, A; Grallert, H; Grammer, TB; Gräßler, J; Grewal, J; Groves, Christopher J.; Haller, T; Hallmans, G; Hartman, CA; Hassinen, M; Hayward, C; Heikkilä, K; Herzig, KH; Helmer, Q; Hillege, Hans; Holmen, O; Hunt, SC; Isaacs, A; Ittermann, T; James, AL; Johansson, I; Juliusdottir, T; Kalafati, IP; Kinnunen, L; Koenig, W; Kooner, IK; Kratzer, W; Lamina, C; Leander, K; Lee, NR; Lichtner, P; Lind, L; Lindström, J; Lobbens, S; Lorentzon, M; Mach, F; Magnusson, PK; Mahajan, A; McArdle, WL; Menni, C; Merger, S; Mihailov, E; Milani, L; Mills, R; Moayyeri, A; Monda, KL; Mooijaart, SP; Mühleisen, TW; Mulas, A; Müller, G; Müller-Nurasyid, M; Nagaraja, R; Nalls, MA; Narisu, N; Glorioso, N; Nolte, IM; Olden, M; Rayner, NW; Renstrom, F; Ried, JS; Robertson, NR; Rose, LM; Sanna, S; Scharnagl, H; Scholtens, S; Sennblad, B; Seufferlein, T; Sitlani, CM; Vernon Smith, A; Stirrups, K; Stringham, HM; Sundström, J; Swertz, MA; Swift, AJ; Syvänen, AC; Tayo, BO; Thorand, B; Thorleifsson, G; Tomaschitz, A; Troffa, C; van Oort, FV; Verweij, N; Vonk, JM; Waite, LL; Wennauer, R; Wilsgaard, T; Wojczynski, MK; Wong, A; Zhang, Q; Hua Zhao, J; Brennan, EP; Choi, M; Eriksson, P; Folkersen, L; Franco-Cereceda, A; Gharavi, AG; Hedman, ÅK; Hivert, MF; Huang, J; Kanoni, S; Karpe, F; Keildson, S; Kiryluk, K; Liang, L; Lifton, RP; Ma, B; McKnight, AJ; McPherson, R; Metspalu, A; Min, JL; Moffatt, MF; Montgomery, GW; Murabito, JM; Nicholson, G; Nyholt, DR; Olsson, C; Perry, John R.B.; Reinmaa, E; Salem, RM; Sandholm, N; Schadt, EE; Scott, RA; Stolk, L; Vallejo, EE; Westra, HJ; Zondervan, KT; ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium; Amouyel, P; Arveiler, D; Bakker, SJ; Beilby, J; Bergman, RN; Blangero, J; Brown, MJ; Burnier, M; Campbell, H; Chakravarti, A; Chines, PS; Claudi-Boehm, S; Collins, FS; Crawford, DC; Danesh, J; de Faire, U; de Geus, Eco; Dörr, M; Erbel, R; Eriksson, Johan G.; Farrall, M; Ferrannini, E; Ferrières, J; Forouhi, NG; Forrester, T; Franco, OH; Gansevoort, RT; Gieger, C; Gudnason, V; Haiman, CA; Harris, Tamara; Hattersley, Andrew T.; Heliövaara, M; Hicks, AA; Hingorani, Aroon; Hoffmann, W; Hofman, A; Homuth, G; Humphries, SE; Hyppönen, E; Illig, T; Jarvelin, MR; Johansen, B; Jousilahti, P; Jula, AM; Kaprio, J; Kee, F; Keinanen-Kiukaanniemi, SM; Kooner, JS; Kooperberg, C; Kovacs, P; Kraja, AT; Kumari, M; Kuulasmaa, K; Kuusisto, J; Lakka, TA; Langenberg, C; Le Marchand, L; Lehtimäki, T; Lyssenko, V; Männistö, S; Marette, A; Matise, TC; McKenzie, CA; McKnight, B; Musk, AW; Möhlenkamp, S; Morris, AD; Nelis, M; Ohlsson, C; Oldehinkel, AJ; Ong, KK; Palmer, LJ; Penninx, BW; Peters, A; Pramstaller, PP; Raitakari, OT; Rankinen, T; Rao, DC; Rice, TK; Ridker, PM; Ritchie, MD; Rudan, I; Salomaa, V; Samani, NJ; Saramies, J; Sarzynski, MA; Schwarz, PE; Shuldiner, AR; Staessen, JA; Steinthorsdottir, V; Stolk, RP; Strauch, K; Tönjes, A; Tremblay, A; Tremoli, E; Vohl, MC; Völker, U; Vollenweider, P; Wilson, JF; Witteman, JC; Adair, LS; Bochud, M; Boehm, BO; Bornstein, SR; Bouchard, C; Cauchi, S; Caulfield, MJ; Chambers, JC; Chasman, DI; Cooper, RS; Dedoussis, George V.; Ferrucci, L; Froguel, P; Grabe, HJ; Hamsten, A; Hui, J; Hveem, K; Jöckel, KH; Kivimaki, M; Kuh, D; Laakso, M; Liu, Y; März, W; Munroe, PB; Njølstad, I; Oostra, BA; Palmer, CN; Pedersen, NL; Perola, M; Pérusse, L; Peters, U; Power, C; Quertermous, T; Rauramaa, R; Rivadeneira, F; Saaristo, TE; Saleheen, D; Sinisalo, J; Slagboom, PE; Snieder, H; Spector, TD; Thorsteinsdottir, U; Stumvoll, M; Tuomilehto, J; Uitterlinden, AG; Uusitupa, M; van der Harst, P; Veronesi, G; Walker, M; Wareham, NJ; Watkins, H; Wichmann, HE; Abecasis, GR; Assimes, TL; Berndt, SI; Boehnke, M; Borecki, IB; Deloukas, P; Franke, L; Frayling, Timothy M.; Groop, Leif; Hunter, DJ; Kaplan, RC; O'Connell, JR; Qi, L; Schlessinger, D; Strachan, DP; Stefansson, K; van Duijn, CM; Willer, CJ; Visscher, PM; Yang, J; Hirschhorn, JN; Zillikens, MC; McCarthy, MI; Speliotes, EK; North, KE; Fox, CS; Barroso, I; Franks, PW; Ingelsson, E; Heid, IM; Loos, RJ; Cupples, LA; Morris, AP; Lindgren, CM; Mohlke, KL

Date: 11 February 2015

http://hdl.handle.net/10871/18163

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Article

Journal

Nature

Publisher

Nature Publishing Group