| dc.contributor.author | O'Connell, SM | |
| dc.contributor.author | Proks, P | |
| dc.contributor.author | Kramer, H | |
| dc.contributor.author | Mattis, KK | |
| dc.contributor.author | Sachse, G | |
| dc.contributor.author | Joyce, C | |
| dc.contributor.author | Houghton, JA | |
| dc.contributor.author | Ellard, S | |
| dc.contributor.author | Hattersley, Andrew T. | |
| dc.contributor.author | Ashcroft, FM | |
| dc.contributor.author | O'Riordan, SM | |
| dc.date.accessioned | 2016-01-29T10:36:04Z | |
| dc.date.issued | 2015-09-08 | |
| dc.description.abstract | In infants, especially with novel previously undescribed mutations of the KATP channel causing neonatal diabetes, in vitro studies can be used to both predict the response to sulphonylurea treatment and support a second trial of glibenclamide at higher than standard doses if the expected response is not observed. | en_GB |
| dc.identifier.citation | Vol. 3, Iss. 10, pp. 884 - 887 | en_GB |
| dc.identifier.doi | 10.1002/ccr3.370 | |
| dc.identifier.uri | http://hdl.handle.net/10871/19423 | |
| dc.language.iso | en | en_GB |
| dc.publisher | Wiley Open Access | en_GB |
| dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/26509030 | en_GB |
| dc.relation.url | http://onlinelibrary.wiley.com/doi/10.1002/ccr3.370/abstract | en_GB |
| dc.rights | © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. | en_GB |
| dc.subject | Glibenclamide | en_GB |
| dc.subject | K-ATP channel | en_GB |
| dc.subject | in vitro | en_GB |
| dc.subject | neonatal diabetes | en_GB |
| dc.title | The value of in vitro studies in a case of neonatal diabetes with a novel Kir6.2-W68G mutation. | en_GB |
| dc.type | Article | en_GB |
| dc.date.available | 2016-01-29T10:36:04Z | |
| dc.identifier.issn | 2050-0904 | |
| exeter.place-of-publication | England | |
| dc.description | Journal Article | en_GB |
| dc.description | This is an open access article available at http://onlinelibrary.wiley.com/doi/10.1002/ccr3.370/full | en_GB |
| dc.identifier.eissn | 2050-0904 | |
| dc.identifier.journal | Clinical Case Reports | en_GB |
