dc.contributor.author | Qureshi, Nadeem | |
dc.contributor.author | Armstrong, S | |
dc.contributor.author | Saukko, Paula M. | |
dc.contributor.author | Sach, T | |
dc.contributor.author | Middlemass, J | |
dc.contributor.author | Evans, Philip H | |
dc.contributor.author | Kai, J | |
dc.contributor.author | Farrimond, Hannah | |
dc.contributor.author | Humphries, SE | |
dc.date.accessioned | 2016-02-12T10:41:38Z | |
dc.date.issued | 2009-10-12 | |
dc.description.abstract | BACKGROUND: Coronary heart disease (CHD) is the leading cause of death in the developed world, and its prevention a core activity in current UK general practice. Currently, family history is not systematically integrated into cardiovascular risk assessment in the UK, Europe or the US. Further, primary health care professionals' lack the confidence to interpret family history information and there is a low level of recording of family history information in General Practice (GP) records. Primary prevention of CHD through lifestyle advice has sometimes yielded modest results although, for example, behavioural interventions targeted at "at risk" patients have produced encouraging findings. A family history approach, targeted at those requesting CHD assessment, could motivate lifestyle change. The project will assess the clinical value of incorporating systematic family history information into CHD risk assessment in primary care, from the perspective of the users of this service, the health care practitioners providing this service, and the National Health Service. METHODS/DESIGN: The study will include three distinct phases: (1) cross-sectional survey to ascertain baseline information on current recording of family information; (2) through an exploratory matched-pair cluster randomised study, with nested qualitative semi-structured interview and focus group study, to assess the impact of systematic family history recording on participants' and primary care professionals' experience; (3) develop an economic model of the costs and benefits of incorporating family history into CHD risk assessment. DISCUSSION: On completion of the project, users and primary care practitioners will be more informed of the value and utility of including family history in CHD risk assessment. Further, this approach will also act as a model of how familial risk information can be integrated within mainstream primary care preventive services for common chronic diseases. TRIAL REGISTRATION: Current Controlled Trials ISRCTN17943542. | en_GB |
dc.description.sponsorship | Department of Health Genetic Health Service Research programme | en_GB |
dc.description.sponsorship | US economic and Social Research Council's Genomics in Society Research Programme | en_GB |
dc.identifier.citation | Vol. 9, pp. 184 - | en_GB |
dc.identifier.doi | 10.1186/1472-6963-9-184 | |
dc.identifier.other | 1472-6963-9-184 | |
dc.identifier.uri | http://hdl.handle.net/10871/19769 | |
dc.language.iso | en | en_GB |
dc.publisher | BioMed Central | en_GB |
dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/19821989 | en_GB |
dc.relation.url | http://bmchealthservres.biomedcentral.com/articles/10.1186/1472-6963-9-184 | en_GB |
dc.rights | Copyright © 2009 Qureshi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | en_GB |
dc.subject | Coronary Disease | en_GB |
dc.subject | Cross-Sectional Studies | en_GB |
dc.subject | Focus Groups | en_GB |
dc.subject | Genetic Predisposition to Disease | en_GB |
dc.subject | Great Britain | en_GB |
dc.subject | Humans | en_GB |
dc.subject | Interviews as Topic | en_GB |
dc.subject | Life Style | en_GB |
dc.subject | Medical History Taking | en_GB |
dc.subject | Primary Health Care | en_GB |
dc.subject | Primary Prevention | en_GB |
dc.subject | Risk Assessment | en_GB |
dc.subject | State Medicine | en_GB |
dc.title | Realising the potential of the family history in risk assessment and primary prevention of coronary heart disease in primary care: ADDFAM study protocol. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2016-02-12T10:41:38Z | |
dc.identifier.issn | 1472-6963 | |
exeter.place-of-publication | England | |
dc.description | Published online | en_GB |
dc.description | Journal Article | en_GB |
dc.description | Randomized Controlled Trial | en_GB |
dc.description | Research Support, Non-U.S. Gov't | en_GB |
dc.identifier.journal | BMC Health Services Research | en_GB |