dc.contributor.author | Hamilton, F | |
dc.contributor.author | Carroll, R | |
dc.contributor.author | Hamilton, W | |
dc.contributor.author | Salisbury, C | |
dc.date.accessioned | 2016-06-30T14:16:29Z | |
dc.date.issued | 2014-08-05 | |
dc.description.abstract | BACKGROUND: The risk of cancer with hypercalcaemia in primary care is unknown. METHODS: This was a cohort study using calcium results in patients aged ⩾40 years in a primary care electronic data set. Diagnoses of cancer in the following year were identified. RESULTS: Participants (54 267) had calcium results: 1674 (3%) were ⩾2.6 mmol l(-1). Hypercalcaemia was strongly associated with cancer, especially in males: OR 2.92, 95% CI 2.17-3.93, P=<0.001; positive predictive value (PPV) 11.5%; females: OR 1.86, 95% CI 1.39-2.50, P<0.001: PPV 4.1%. CONCLUSIONS: Hypercalcaemia is strongly associated with cancer in primary care, with men at most risk, despite hypercalcaemia being more common in women. | en_GB |
dc.identifier.citation | Vol. 111, pp. 1410 - 1412 | en_GB |
dc.identifier.doi | 10.1038/bjc.2014.433 | |
dc.identifier.other | bjc2014433 | |
dc.identifier.uri | http://hdl.handle.net/10871/22341 | |
dc.language.iso | en | en_GB |
dc.publisher | Cancer Research UK | en_GB |
dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/25093495 | en_GB |
dc.relation.url | http://www.nature.com/bjc/journal/v111/n7/full/bjc2014433a.html | en_GB |
dc.rights | This is the final version of the article. Available from Cancer Research UK via the DOI in this record. | en_GB |
dc.subject | Aged | en_GB |
dc.subject | Aged, 80 and over | en_GB |
dc.subject | Case-Control Studies | en_GB |
dc.subject | Electronic Health Records | en_GB |
dc.subject | Female | en_GB |
dc.subject | Humans | en_GB |
dc.subject | Hypercalcemia | en_GB |
dc.subject | Incidence | en_GB |
dc.subject | Male | en_GB |
dc.subject | Middle Aged | en_GB |
dc.subject | Multivariate Analysis | en_GB |
dc.subject | Neoplasms | en_GB |
dc.subject | Primary Health Care | en_GB |
dc.subject | Retrospective Studies | en_GB |
dc.subject | Risk Factors | en_GB |
dc.title | The risk of cancer in primary care patients with hypercalcaemia: a cohort study using electronic records. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2016-06-30T14:16:29Z | |
dc.identifier.issn | 0007-0920 | |
exeter.place-of-publication | England | en_GB |
dc.description | Published | en_GB |
dc.description | Journal Article | en_GB |
dc.identifier.eissn | 1532-1827 | |
dc.identifier.journal | British Journal of Cancer | en_GB |