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dc.contributor.authorUpile, T
dc.contributor.authorJerjes, WK
dc.contributor.authorSterenborg, HJ
dc.contributor.authorWong, BJ
dc.contributor.authorEl-Naggar, AK
dc.contributor.authorIlgner, JF
dc.contributor.authorSandison, A
dc.contributor.authorWitjes, MJ
dc.contributor.authorBiel, MA
dc.contributor.authorvan Veen, R
dc.contributor.authorHamdoon, Z
dc.contributor.authorGillenwater, A
dc.contributor.authorMosse, CA
dc.contributor.authorRobinson, DJ
dc.contributor.authorBetz, CS
dc.contributor.authorStepp, H
dc.contributor.authorBolotine, L
dc.contributor.authorMcKenzie, G
dc.contributor.authorBarr, H
dc.contributor.authorChen, Z
dc.contributor.authorBerg, K
dc.contributor.authorD'Cruz, AK
dc.contributor.authorSudhoff, H
dc.contributor.authorStone, N
dc.contributor.authorKendall, C
dc.contributor.authorFisher, S
dc.contributor.authorMacRobert, AJ
dc.contributor.authorLeunig, A
dc.contributor.authorOlivo, M
dc.contributor.authorRichards-Kortum, R
dc.contributor.authorSoo, KC
dc.contributor.authorBagnato, V
dc.contributor.authorChoo-Smith, L-P
dc.contributor.authorSvanberg, K
dc.contributor.authorTan, IB
dc.contributor.authorWilson, BC
dc.contributor.authorWolfsen, H
dc.contributor.authorBigio, I
dc.contributor.authorYodh, AG
dc.contributor.authorHopper, C
dc.date.accessioned2017-02-09T09:13:03Z
dc.date.issued2011-02-09
dc.description.abstractThe complete surgical removal of disease is a desirable outcome particularly in oncology. Unfortunately much disease is microscopic and difficult to detect causing a liability to recurrence and worsened overall prognosis with attendant costs in terms of morbidity and mortality. It is hoped that by advances in optical diagnostic technology we could better define our surgical margin and so increase the rate of truly negative margins on the one hand and on the other hand to take out only the necessary amount of tissue and leave more unaffected non-diseased areas so preserving function of vital structures. The task has not been easy but progress is being made as exemplified by the presentations at the 2nd Scientific Meeting of the Head and Neck Optical Diagnostics Society (HNODS) in San Francisco in January 2010. We review the salient advances in the field and propose further directions of investigation.en_GB
dc.identifier.citationVol. 3, pp. 7 -en_GB
dc.identifier.doi10.1186/1758-3284-3-7
dc.identifier.other1758-3284-3-7
dc.identifier.urihttp://hdl.handle.net/10871/25719
dc.language.isoenen_GB
dc.publisherOpen Access Publishing Londonen_GB
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/21306627en_GB
dc.rightsCopyright © Upile et al; licensee BioMed Central Ltd. 2011 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_GB
dc.subjectBiopsyen_GB
dc.subjectDiagnostic Techniques and Proceduresen_GB
dc.subjectGeneral Surgeryen_GB
dc.subjectHeaden_GB
dc.subjectHumansen_GB
dc.subjectNecken_GB
dc.subjectPhotochemotherapyen_GB
dc.subjectTomography, Optical Coherenceen_GB
dc.titleAt the frontiers of surgery: review.en_GB
dc.typeArticleen_GB
dc.date.available2017-02-09T09:13:03Z
exeter.place-of-publicationEnglanden_GB
dc.descriptionPublished onlineen_GB
dc.descriptionCongressesen_GB
dc.descriptionThis is the final version of the article. Available from Open Access Publishing London via the DOI in this record.en_GB
dc.identifier.eissn1758-3284
dc.identifier.journalHead and Neck Oncologyen_GB


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