dc.contributor.author | Archer, CR | |
dc.contributor.author | Stephens, RM | |
dc.contributor.author | Sharma, MD | |
dc.contributor.author | Hosken, DJ | |
dc.date.accessioned | 2017-07-27T14:05:54Z | |
dc.date.issued | 2017-07-13 | |
dc.description.abstract | The Y chromosome should degenerate because it cannot recombine. However, male limited transmission increases selection efficiency for male benefit alleles on the Y, and therefore Y-chromosomes should contribute significantly to variation in male-fitness. This means that although the Drosophila Y chromosome is small and gene-poor, Y-linked genes are vital for male fertility in D. melanogaster and the Y chromosome has large male-fitness effects. It is unclear if the same pattern is seen in the closely related D. simulans. We backcrossed Y chromosomes from 3 geographic locations into 5 genetic backgrounds and found strong Y and genetic background effects on male fertility. There was a significant Y-background interaction, indicating substantial epistasis between the Y and autosomal genes affecting male fertility. This supports accumulating evidence that interactions between the Y chromosome and the autosomes are key determinants of male fitness. This article is protected by copyright. All rights reserved. | en_GB |
dc.description.sponsorship | DJH was funded by The Leverhulme Trust. | en_GB |
dc.identifier.citation | Accepted manuscript online 13 July 2017 | en_GB |
dc.identifier.doi | 10.1111/jeb.13141 | |
dc.identifier.uri | http://hdl.handle.net/10871/28675 | |
dc.language.iso | en | en_GB |
dc.publisher | Wiley | en_GB |
dc.rights.embargoreason | Publisher policy | en_GB |
dc.subject | Drosophila simulans | en_GB |
dc.subject | ebony | en_GB |
dc.subject | Y chromosome | en_GB |
dc.subject | co-evolution | en_GB |
dc.subject | fertility | en_GB |
dc.title | The Drosophila simulans Y chromosome interacts with the autosomes to influence male fitness. | en_GB |
dc.type | Article | en_GB |
dc.identifier.issn | 1010-061X | |
exeter.place-of-publication | Switzerland | en_GB |
dc.description | This is the author's accepted manuscript | en_GB |
dc.description | The final version is available from Wiley via the DOI in this record | en_GB |
dc.identifier.eissn | 1420-9101 | |
dc.identifier.journal | Journal of Evolutionary Biology | en_GB |
dc.identifier.pmid | 28703322 | |