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dc.contributor.authorDas, S
dc.contributor.authorMaharatna, K
dc.date.accessioned2018-01-19T16:00:36Z
dc.date.issued2013-08-30
dc.description.abstractIn this paper, an incommensurate fractional order (FO) model has been proposed to generate ECG like waveforms. Earlier investigation of ECG like waveform generation is based on two identical Van-der Pol (VdP) family of oscillators, which are coupled by time delays and gains. In this paper, we suitably modify the three state equations corresponding to the nonlinear cross-product of states, time delay coupling of the two oscillators and low-pass filtering, using the concept of fractional derivatives. Our results show that a wide variety of ECG like waveforms can be simulated from the proposed generalized models, characterizing heart conditions under different physiological conditions. Such generalization of the modelling of ECG waveforms may be useful to understand the physiological process behind ECG signal generation in normal and abnormal heart conditions. Along with the proposed FO models, an optimization based approach is also presented to estimate the VdP oscillator parameters for representing a realistic ECG like signal.en_GB
dc.description.sponsorshipThe work presented in this paper was supported by the E.U. ARTEMIS Joint Undertaking under the Cyclic and Person-Centric Health Management: Integrated appRoach for hOme, mobile and clinical eNvironments – (CHIRON) Project, Grant Agreement # 2009-1-100228.en_GB
dc.identifier.citationVol. 112 (3), pp. 490 - 507en_GB
dc.identifier.doi10.1016/j.cmpb.2013.08.012
dc.identifier.urihttp://hdl.handle.net/10871/31113
dc.language.isoenen_GB
dc.publisherElsevieren_GB
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/24028797en_GB
dc.rightsCopyright © 2013 Elsevier Ireland Ltd. All rights reserved.en_GB
dc.subjectDelay differential equation (DDE)en_GB
dc.subjectElectrocardiogram (ECG)en_GB
dc.subjectFractional calculusen_GB
dc.subjectPhase spaceen_GB
dc.subjectVan-der Pol (VdP) oscillatoren_GB
dc.subjectElectrocardiographyen_GB
dc.subjectHumansen_GB
dc.subjectModels, Theoreticalen_GB
dc.titleFractional dynamical model for the generation of ECG like signals from filtered coupled Van-der Pol oscillatorsen_GB
dc.typeArticleen_GB
dc.date.available2018-01-19T16:00:36Z
exeter.place-of-publicationIrelanden_GB
dc.descriptionThis is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.en_GB
dc.identifier.journalComputer Methods and Programs in Biomedicineen_GB


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