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Enhanced deep detection of Raman scattered light by wavefront shaping

dc.contributor.authorPaniagua-Diaz, AM
dc.contributor.authorGhita, A
dc.contributor.authorVettenburg, T
dc.contributor.authorStone, N
dc.contributor.authorBertolotti, J
dc.date.accessioned2018-12-04T15:24:43Z
dc.date.issued2018-12-10
dc.description.abstractLight scattering limits the penetration depth of non-invasive Raman spectroscopy in biological media. While safe levels of irradiation may be adequate to analyze superficial tissue, scattering of the pump beam reduces the Raman signal to undetectable levels deeper within the tissue. Here we demonstrate how wavefront shaping techniques can significantly increase the Raman signal at depth, while keeping the total irradiance constant, thus increasing the amount of Raman signal available for detection.en_GB
dc.description.sponsorshipEngineering and Physical Sciences Research Council (EPSRC)en_GB
dc.description.sponsorshipLeverhulme Trusten_GB
dc.identifier.citationVol. 26 (26), pp. 33565-33574.en_GB
dc.identifier.doi10.1364/OE.26.033565
dc.identifier.grantnumberEP/L015331/1en_GB
dc.identifier.grantnumberEP/P012442/1en_GB
dc.identifier.grantnumberRPG-2016-129en_GB
dc.identifier.urihttp://hdl.handle.net/10871/34990
dc.language.isoenen_GB
dc.publisherOptical Society of America (OSA)en_GB
dc.relation.urlhttp://hdl.handle.net/10871/35783
dc.rightsJournal © 2018. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.
dc.titleEnhanced deep detection of Raman scattered light by wavefront shapingen_GB
dc.typeArticleen_GB
dc.date.available2018-12-04T15:24:43Z
dc.identifier.issn1094-4087
dc.relation.isreplacedby10871/35783
dc.relation.isreplacedbyhttp://hdl.handle.net/10871/35783
dc.descriptionThis is the author accepted manuscript. The final version is available from the Optical Society of America (OSA) via the DOI in this record.en_GB
dc.descriptionThere is another ORE record for this publication: http://hdl.handle.net/10871/35783
dc.identifier.journalOptics Expressen_GB
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_GB
dcterms.dateAccepted2018-11-14
rioxxterms.versionAMen_GB
rioxxterms.licenseref.startdate2018-11-14
rioxxterms.typeJournal Article/Reviewen_GB
refterms.dateFCD2018-12-03T14:12:50Z
refterms.versionFCDAM
refterms.dateFOA2018-12-20T11:32:35Z
refterms.panelBen_GB


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Journal © 2018. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.
Except where otherwise noted, this item's licence is described as Journal © 2018. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.