Upconversion raster scanning microscope for long-wavelength infrared imaging of breast cancer microcalcifications
Tseng, YP; Bouzy, P; Pedersen, C; et al.Stone, N; Tidemand-Lichtenberg, P
Date: 24 September 2018
Journal
Biomedical Optics Express
Publisher
Optical Society of America
Publisher DOI
Abstract
Long-wavelength identification of microcalcifications in breast cancer tissue is demonstrated using a novel upconversion raster scanning microscope. The system consists of quantum cascade lasers (QCL) for illumination and an upconversion system for efficient, high-speed detection using a silicon detector. Absorbance spectra and images ...
Long-wavelength identification of microcalcifications in breast cancer tissue is demonstrated using a novel upconversion raster scanning microscope. The system consists of quantum cascade lasers (QCL) for illumination and an upconversion system for efficient, high-speed detection using a silicon detector. Absorbance spectra and images of regions of ductal carcinoma in situ (DCIS) from the breast have been acquired using both upconversion and Fourier-transform infrared (FTIR) systems. The spectral images are compared and good agreement is found between the upconversion and the FTIR systems.
Physics and Astronomy
Faculty of Environment, Science and Economy
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