Brillouin microspectroscopy data of tissue-mimicking gelatin hydrogels
dc.contributor.author | Bailey, M | |
dc.contributor.author | Correa, N | |
dc.contributor.author | Harding, S | |
dc.contributor.author | Stone, N | |
dc.contributor.author | Brasselet, S | |
dc.contributor.author | Palombo, F | |
dc.date.accessioned | 2020-02-10T10:23:38Z | |
dc.date.issued | 2020-02-08 | |
dc.description.abstract | Brillouin spectroscopy, based on the inelastic scattering of light from thermally driven acoustic waves or phonons [1], holds great promise in the field of life sciences as it provides functionally relevant micromechanical information in a contactless all-optical manner [2]. Due to the complexity of biological systems such as cells and tissues, which present spatio-temporal heterogeneities, interpretation of Brillouin spectra can be difficult. The data presented here were collected from gelatin hydrogels, used as tissue-mimicking model systems for Brillouin microspectroscopy measurements conducted using a lab-built Brillouin microscope with a dual-stage VIPA spectrometer. By varying the solute concentration in the range 4 to 18% (w/w), the macroscopic mechanical properties of the hydrogels can be tuned and the corresponding evolution in the Brillouin-derived longitudinal elastic modulus measured. An increase in Brillouin frequency shift with increasing solute concentration was observed, which was found to correlate with an increase in acoustic wave velocity and longitudinal modulus. The gels used here provide a viable model system for benchmarking and standardisation, and the data will be useful for spectrometer development and validation. | en_GB |
dc.description.sponsorship | Engineering and Physical Sciences Research Council (EPSRC) | en_GB |
dc.description.sponsorship | Cancer Research UK | en_GB |
dc.identifier.citation | Article 105267 | en_GB |
dc.identifier.doi | 10.1016/j.dib.2020.105267 | |
dc.identifier.grantnumber | EP/M028739/1 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/40796 | |
dc.language.iso | en | en_GB |
dc.publisher | Elsevier | en_GB |
dc.relation.url | https://doi.org/10.24378/exe.2144 | en_GB |
dc.rights | © Elsevier 2020. This version is made available under the CC-BY-NC-ND 4.0 license | en_GB |
dc.subject | Brillouin scattering | en_GB |
dc.subject | Phonons | en_GB |
dc.subject | Biopolymers | en_GB |
dc.subject | Tissue phantoms | en_GB |
dc.subject | Collagen | en_GB |
dc.subject | Biomechanics | en_GB |
dc.title | Brillouin microspectroscopy data of tissue-mimicking gelatin hydrogels | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2020-02-10T10:23:38Z | |
dc.identifier.issn | 2352-3409 | |
exeter.article-number | 105267 | en_GB |
dc.description | This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record | en_GB |
dc.description | Data identification number: 10.24378/exe.2144 Direct URL to data: https://doi.org/10.24378/exe.2144 | en_GB |
dc.identifier.journal | Data in Brief | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | en_GB |
dcterms.dateAccepted | 2020-02-03 | |
exeter.funder | ::Engineering and Physical Sciences Research Council (EPSRC) | en_GB |
exeter.funder | ::Cancer Research UK | en_GB |
rioxxterms.version | AM | en_GB |
rioxxterms.licenseref.startdate | 2020-02-08 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2020-02-10T10:08:49Z | |
refterms.versionFCD | AM | |
refterms.dateFOA | 2020-02-10T10:23:42Z | |
refterms.panel | B | en_GB |
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