| dc.contributor.author | Harries, LW | |
| dc.contributor.author | Bradley-Smith, Rachel | |
| dc.contributor.author | Llewellyn, DJ | |
| dc.contributor.author | Pilling, LC | |
| dc.contributor.author | Fellows, A | |
| dc.contributor.author | Henley, William E. | |
| dc.contributor.author | Hernandez, Dena | |
| dc.contributor.author | Guralnik, Jack | |
| dc.contributor.author | Bandinelli, S | |
| dc.contributor.author | Singleton, A | |
| dc.contributor.author | Ferrucci, L | |
| dc.contributor.author | Melzer, D | |
| dc.date.accessioned | 2013-04-19T15:37:13Z | |
| dc.date.issued | 2012-08 | |
| dc.description.abstract | Circulating inflammatory markers may play an important role in cognitive impairment at older ages. Mice deficient for the chemokine (C-C motif) receptor 2 (CCR2) develop an accelerated Alzheimer-like pathology. CCR2 is also important in neurogenesis. To identify human gene transcripts most closely associated with Mini-Mental State Examination (MMSE) scores, we undertook a genome-wide and inflammation specific transcriptome screen in circulating leukocytes from a population-based sample. | en_GB |
| dc.identifier.citation | Vol. 15, Issue 4, pp. 395 - 404 | en_GB |
| dc.identifier.doi | 10.1089/rej.2011.1302 | |
| dc.identifier.uri | http://hdl.handle.net/10871/8382 | |
| dc.language.iso | en | en_GB |
| dc.publisher | Mary Ann Liebert | en_GB |
| dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/22607625 | en_GB |
| dc.title | Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults | en_GB |
| dc.type | Article | en_GB |
| dc.date.available | 2013-04-19T15:37:13Z | |
| exeter.place-of-publication | United States | |
| dc.description | This is a copy of an article published in Rejuvenation Research © 2012 Mary Ann Liebert, Inc.; Rejuvenation Research is available online at: http://online.liebertpub.com. | en_GB |
| dc.identifier.journal | Rejuvenation Research | en_GB |
