The Badger Vaccine Deployment Project: year one analysis aiding an adaptive management approach for increasing efficiency
Allsop, Thomas John
Date: 18 October 2011
Thesis or dissertation
University of Exeter
MbyRes in Biosciences
Bovine tuberculosis (bTB) in cattle is considered one of the UK’s most serious animal health problems and the European badger (Meles meles) is widely implemented as the most important wildlife reservoir of the disease. The use of a Bacillus Calmette-Guérin (BCG) vaccination has shown to reduce the progression, severity and excretion ...
Bovine tuberculosis (bTB) in cattle is considered one of the UK’s most serious animal health problems and the European badger (Meles meles) is widely implemented as the most important wildlife reservoir of the disease. The use of a Bacillus Calmette-Guérin (BCG) vaccination has shown to reduce the progression, severity and excretion of bTB in badgers. The first year of The Badger Vaccine Deployment Project, utilising the BCG vaccine, has recently concluded and this study acted to investigate factors affecting the efficiency of such a large scale vaccination campaign. Analysis revealed that key differences in operatives trapping behaviour, notably the number of traps sited and location of trapping, affected the number of badgers vaccinated and each individual operatives capture rate (a measure of trapping success per unit effort). Additionally capture rate declined differently between traps on setts and those placed remotely, suggesting simple alterations in the number of traps sited and/or number of times certain locations are trapped could increase the total number of badgers vaccinated. Adopting an adaptive management approach, whereby we analyse factors that affected the number of badgers vaccinated, learn from these findings, and adjust future behaviour, will be key to an effective and efficient badger vaccination campaign.
Item views 0
Full item downloads 0
Showing items related by title, author, creator and subject.
Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes Peacock, SJ; Limmathurotsakul, D; Lubell, Y; et al. (Public Library of Science, 1 January 2012)BACKGROUND: Burkholderia pseudomallei is a Category B select agent and the cause of melioidosis. Research funding for vaccine development has largely considered protection within the biothreat context, but the resulting ...
BCG vaccination reduces risk of tuberculosis infection in vaccinated badgers and unvaccinated badger cubs Carter, SP; Chambers, MA; Rushton, SP; et al. (Public Library of Science, 12 December 2012)Wildlife is a global source of endemic and emerging infectious diseases. The control of tuberculosis (TB) in cattle in Britain and Ireland is hindered by persistent infection in wild badgers (Meles meles). Vaccination with ...
The long-term safety, public health impact, and cost-effectiveness of routine vaccination with a recombinant, live-attenuated dengue vaccine (Dengvaxia): a model comparison study Flasche, Stefan; Jit, Mark; Rodríguez-Barraquer, Isabel; et al. (Public Library of Science (PLoS), 29 November 2016)Background: Large Phase III trials across Asia and Latin America have recently demonstrated the efficacy of a recombinant, live-attenuated dengue vaccine (Dengvaxia) over the first 25 mo following vaccination. Subsequent ...