Microfluidic devices powered by integrated elasto-magnetic pumps (article)
dc.contributor.author | Binsley, JL | |
dc.contributor.author | Martin, EL | |
dc.contributor.author | Myers, TO | |
dc.contributor.author | Pagliara, S | |
dc.contributor.author | Ogrin, FY | |
dc.date.accessioned | 2020-10-27T14:07:15Z | |
dc.date.issued | 2020-10-23 | |
dc.description.abstract | We show how an asymmetric elasto-magnetic system provides a novel integrated pumping solution for lab-on-a-chip and point of care devices. This monolithic pumping solution, inspired by Purcell's 3-link swimmer, is integrated within a simple microfluidic device, bypassing the requirement of external connections. We experimentally prove that this system can provide tuneable fluid flow with a flow rate of up to 600 μL h-1. This fluid flow is achieved by actuating the pump using a weak, uniform, uniaxial, oscillating magnetic field, with field amplitudes in the range of 3-6 mT. Crucially, the fluid flow can be reversed by adjusting the driving frequency. We experimentally prove that this device can successfully operate on fluids with a range of viscosities, where pumping at higher viscosity correlates with a decreasing optimal driving frequency. The fluid flow produced by this device is understood here by examining the non-reciprocal motion of the elasto-magnetic component. This device has the capability to replace external pumping systems with a simple, integrated, lab-on-a-chip component. | en_GB |
dc.description.sponsorship | Engineering and Physical Sciences Research Council (EPSRC) | en_GB |
dc.description.sponsorship | European Union Horizon 2020 | en_GB |
dc.description.sponsorship | Medical Research Council (MRC) | en_GB |
dc.description.sponsorship | Royal Society | en_GB |
dc.description.sponsorship | Wellcome Trust | en_GB |
dc.identifier.citation | Published online 23 October 2020 | en_GB |
dc.identifier.doi | 10.1039/d0lc00935k | |
dc.identifier.grantnumber | EP/L015331/1 | en_GB |
dc.identifier.grantnumber | 665440 | en_GB |
dc.identifier.grantnumber | 801374 | en_GB |
dc.identifier.grantnumber | MCPC17189 | en_GB |
dc.identifier.grantnumber | RG180007 | en_GB |
dc.identifier.grantnumber | WT097835/Z/11/Z | en_GB |
dc.identifier.grantnumber | H2020-MSCA-ITN-2015-675752 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/123389 | |
dc.language.iso | en | en_GB |
dc.publisher | Royal Society of Chemistry | en_GB |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pubmed/33094306 | en_GB |
dc.relation.url | https://doi.org/10.24378/exe.2863 | en_GB |
dc.rights | © The Royal Society of Chemistry 2020. Open Access Article. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. | en_GB |
dc.title | Microfluidic devices powered by integrated elasto-magnetic pumps (article) | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2020-10-27T14:07:15Z | |
exeter.place-of-publication | England | en_GB |
dc.description | This is the final version. Available on open access from the Royal Society of Chemistry via the DOI in this record | en_GB |
dc.description | The dataset associated with this article is located in ORE at: https://doi.org/10.24378/exe.2863 | en_GB |
dc.identifier.eissn | 1473-0189 | |
dc.identifier.journal | Lab on a Chip | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/3.0/ | en_GB |
dcterms.dateAccepted | 2020-10-18 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2020-10-23 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2020-10-27T14:01:47Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2020-10-27T14:07:19Z | |
refterms.panel | B | en_GB |
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Except where otherwise noted, this item's licence is described as © The Royal Society of Chemistry 2020. Open Access Article. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.