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Proton-Pump Inhibitors and Fragility Fractures in Vulnerable Older Patients

dc.contributor.authorZirk-Sadowski, J
dc.contributor.authorMasoli, JA
dc.contributor.authorStrain, WD
dc.contributor.authorDelgado, J
dc.contributor.authorHenley, W
dc.contributor.authorHamilton, W
dc.contributor.authorMelzer, D
dc.contributor.authorBle, A
dc.date.accessioned2017-05-22T13:00:26Z
dc.date.issued2017-03
dc.description.abstractTo the Editor: Proton Pump Inhibitors (PPIs) taken for ≥1 year have been linked to increased fragility fracture (FF) risk, prompting the US FDA to issue a related warning. The oldest old (≥85) and patients with comorbidities may be at greater risk (1); however, little or no evidence has been available in these groups of vulnerable people. In this retrospective-matched cohort study with difference-in-difference methods, we investigated the 4-year FF risk in older patients (≥60) and patients with comorbidities. [...]en_GB
dc.description.sponsorshipThis research is funded by the National Institute for Health Research (NIHR), grant number: PB-PG-0214-3309. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the UK Department of Health.en_GB
dc.identifier.citationVol. 112 (3), pp. 520 - 523en_GB
dc.identifier.doi10.1038/ajg.2016.584
dc.identifier.urihttp://hdl.handle.net/10871/27638
dc.language.isoenen_GB
dc.publisherSpringer Natureen_GB
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/28270664en_GB
dc.rightsOpen access. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.en_GB
dc.titleProton-Pump Inhibitors and Fragility Fractures in Vulnerable Older Patientsen_GB
dc.typeArticleen_GB
dc.date.available2017-05-22T13:00:26Z
exeter.place-of-publicationUnited Statesen_GB
dc.descriptionThis is the author accepted manuscript. Available from Nature Publishing Group via the DOI in this record.en_GB
dc.identifier.journalAmerican Journal of Gastroenterologyen_GB
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/


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Open access. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.
Except where otherwise noted, this item's licence is described as Open access. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.