Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases
Roubroeks, JAY; Smith, RG; van den Hove, DLA; et al.Lunnon, K
Date: 14 August 2017
Article
Journal
Journal of Neurochemistry
Publisher
Wiley
Publisher DOI
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Abstract
Recent studies have suggested a role for epigenetic mechanisms in the complex etiology of various neurodegenerative diseases. In this review, we discuss advances that have been made toward understanding the role of epigenetic processes in neurodegenerative disorders, with a particular focus on Alzheimer's disease, where the most extensive ...
Recent studies have suggested a role for epigenetic mechanisms in the complex etiology of various neurodegenerative diseases. In this review, we discuss advances that have been made toward understanding the role of epigenetic processes in neurodegenerative disorders, with a particular focus on Alzheimer's disease, where the most extensive studies have been undertaken to date. We provide a brief overview of DNA modifications, followed by a summarization of studies of DNA modifications in Alzheimer's disease and other neurodegenerative diseases.
Institute of Biomedical & Clinical Science
Collections of Former Colleges
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